Heidelberg Pharma AG / DE000A11QVV0
15.11.2023 - 09:24:46Heidelberg Pharma Secures Patent for the Use of its ADC Technology Platform
Heidelberg Pharma AG / Key word(s): Patent 15.11.2023 / 09:24 CET/CEST The issuer is solely responsible for the content of this announcement. PRESS RELEASE Ladenburg, Germany, 15 November 2023 – Heidelberg Pharma AG (FSE: HPHA) today announced that its subsidiary Heidelberg Pharma Research GmbH has been granted a patent covering site-specific ATAC conjugates by the European Patent Office (EPO). Site-specific ATAC conjugates comprise a genetically engineered antibody to which Heidelberg Pharma’s proprietary amatoxin payloads can be coupled via specific linkers. The European patent also covers a method for the synthesis of such conjugates as well as their use in the treatment of diseases. It has a term until 2036. ATAC conjugates are antibody drug conjugates (ADCs) based on the toxin Amanitin. The patent protects the use of Amanitin-based ADCs for research and development, as well as for the use in clinical studies and the commercialization of resulting product candidates. Professor Andreas Pahl, Chief Scientific Officer of Heidelberg Pharma, comments: "We are very pleased that this patent has been granted, as it protects essential aspects of our ATAC technology, as e.g. improved safety and tolerability of our product candidates." About Heidelberg Pharma's proprietary ATAC technology Antibody drug conjugates (ADCs) combine the high affinity and specificity of antibodies with the potency of cytotoxic small molecules for the treatment of cancer. ATACs are ADCs whose active ingredient is the mushroom toxin Amanitin. Amanitin inhibits mRNA transcription by binding to RNA polymerase II, a mechanism that is crucial for the survival of eukaryotic cells. In preclinical testing, ATACs have been shown to be highly efficacious, overcoming frequently encountered resistance mechanisms and combating even quiescent tumor cells. About Heidelberg Pharma Heidelberg Pharma is an oncology specialist and the first company to develop the toxin Amanitin into cancer therapies using its proprietary ATAC technology and to advance the biological mode of action of the toxin as a novel therapeutic principle. The proprietary technology platform is being applied to develop the Company’s own therapeutic ATACs as well as in third-party collaborations. The lead candidate HDP-101 is a BCMA ATAC in clinical development for multiple myeloma. Further ATAC candidates are being developed against different targets such as CD37, PSMA and GCC in the indications non-Hodgkin's lymphoma, metastatic castration-resistant prostate cancer or gastrointestinal tumors such as colorectal cancer. Heidelberg Pharma AG is based in Ladenburg, Germany, and is listed on the Frankfurt Stock Exchange: ISIN DE000A11QVV0 / WKN A11QVV / Symbol HPHA. More information is available at www.heidelberg-pharma.com. ATAC® is a registered trademark of Heidelberg Pharma Research GmbH in the EU and the USA.
15.11.2023 CET/CEST Dissemination of a Corporate News, transmitted by EQS News - a service of EQS Group AG. The issuer is solely responsible for the content of this announcement. The EQS Distribution Services include Regulatory Announcements, Financial/Corporate News and Press Releases. Archive at www.eqs-news.com |
Language: | English |
Company: | Heidelberg Pharma AG |
Gregor-Mendel-Str. 22 | |
68526 Ladenburg | |
Germany | |
Phone: | +49 (0)89 41 31 38 - 0 |
Fax: | +49 (0)89 41 31 38 - 99 |
E-mail: | investors@hdpharma.com |
Internet: | www.heidelberg-pharma.com |
ISIN: | DE000A11QVV0 |
WKN: | A11QVV |
Listed: | Regulated Market in Frankfurt (Prime Standard); Regulated Unofficial Market in Berlin, Dusseldorf, Munich, Stuttgart, Tradegate Exchange |
EQS News ID: | 1773615 |
End of News | EQS News Service |
|